In collaboration with the German Cancer Research Center (DKFZ), the Medical Faculty of the Goethe-University announces a new W2 professorship for “Bioinformatics in Oncology” in Frankfurt. Within the field of bioinformatics, she/he will be focussing on oncogenic signal transduction, systems biology and medicine (e.g. data integration) as well as on high throughput experimentation, especially in proteomics. The position will be located at the University Hospital Frankfurt and collaborate with the scientific and clinical research community of the DKTK (www.dktk.org), the DKFZ (www.dkfz.de) and the DKTK partner site Frankfurt / Mainz.
The integration of clinical decision support systems for pharmacogenomic testing into clinical routine has been investigated by the MIRACUM consortium over the last nine months. This joint effort has now resulted in a scoping literature review accepted by BMC Medical Informatics and Decision Making. A total of 12 authors from nine MIRACUM sites provide an overview of the designs of user-system interactions in recent system developments. The final analysis comprises the essence of 32 articles that were identified in a PubMed search. As the most widespread tool, alerts have been identified, next to pharmacogenomic reports, inbox messages, and several more. The authors conclude that i) further evaluation efforts of developed prototypes will be necessary and ii) in the future clinical decision support systems will include prediction models to identify eligible patients for pre-emptive genotyping.
Hinderer M, Boeker M, Wagner SA, Lablans M, Newe S, Hülsemann JL, Neumaier M, Binder H, Renz H, Acker T, Prokosch HU, Sedlmayr M.
Integrating clinical decision support systems for pharmacogenomic testing into clinical routine – a scoping review of designs of user-system interactions in recent system development.
BMC Med Inform Decis Mak. 2017 Jun 6;17(1):81. DOI: 10.1186/s12911-017-0480-y.