{"id":6790,"date":"2022-03-22T11:44:59","date_gmt":"2022-03-22T10:44:59","guid":{"rendered":"https:\/\/miracum.cms.rrze.uni-erlangen.de\/?page_id=6790"},"modified":"2022-04-04T22:02:40","modified_gmt":"2022-04-04T20:02:40","slug":"polar_mi","status":"publish","type":"page","link":"https:\/\/www.miracum.org\/en\/das-konsortium\/projekte\/polar_mi\/","title":{"rendered":"POLAR_MI"},"content":{"rendered":"<h3><span style=\"font-family: helvetica, arial, sans-serif\">Polypharmacy, Drug Interactions and Risks<\/span><\/h3>\n<p><span style=\"font-family: helvetica, arial, sans-serif\">The Use Case \u201cPolypharmacy, Drug Interactions and Risks\u201d (POLypharmazie, Arzneimittelwechselwirkungen und Risiken), which includes all four consortia of the Medical Informatics Initiative, aims to contribute to the detection of health risks in patients with polymedication by using methods and processes of the Medical Informatics Initiative.<\/span><\/p>\n<p><span style=\"font-family: helvetica, arial, sans-serif\">PPolymedication occurs particularly in older patients with multimorbidity. This can lead to drug interactions that either reduce or enhance the desired effect of individual active ingredients or lead to undesired effects due to pharmacological interactions. These can trigger additional clinical pictures and additional need for therapy, which, however, would be avoidable with better drug management.<\/span><\/p>\n<div class=\"rrze-elements accordion style_default\" id=\"accordion-0\">\n<div class=\"button-container-right\"><button class=\"expand-all standard-btn primary-btn xsmall-btn\" data-status=\"closed\">Expand All<\/button><\/div>\n<p><\/p>\n<div class=\"accordion-group fau\">\n<h2 class=\"accordion-heading\"><button class=\"accordion-toggle\" data-toggle=\"collapse\"  href=\"#collapse_0\" aria-expanded=\"false\" aria-controls=\"collapse_0\" id=\"collapse_button_0\"> Goals of POLAR_MI <\/button><\/h2>\n<div id=\"collapse_0\" class=\"accordion-body\" aria-labelledby=\"collapse_button_0\">\n<div class=\"accordion-inner clearfix\">\n<p><span style=\"font-family: helvetica, arial, sans-serif\">In the POLAR_MI Use Case, medical computer scientists, biometricians, epidemiologists, pharmacists, clinical pharmacologists and health researchers from 21 institutions, including 13 university hospitals, work together to<\/span><\/p>\n<p><span style=\"font-family: helvetica, arial, sans-serif\">1) develop and implement methods to collect prospectively and retrospectively available personal data on prescribed drugs (e.g. medication plans) as well as on prescriptions and drug dispensations from pharmacies at several sites of the four MII consortia,<\/span><br \/>\n<span style=\"font-family: helvetica, arial, sans-serif\">2) classify a selected range of polymedications according to available methods regarding Potentially Inadequate Medication (PIM) and a selected range of drugs as high-risk prescriptions,<\/span><br \/>\n<span style=\"font-family: helvetica, arial, sans-serif\">3) electronically map score systems for identifying high-risk patients for relevant drug-related problems, and<\/span><br \/>\n<span style=\"font-family: helvetica, arial, sans-serif\">4) identify the occurrence of adverse drug reactions and their consequences at an early stage or to avoid them completely (e.g. new diagnoses\/interventions, intensive care, re-introduction, new (approved) medications)<\/span><\/p>\n<p><span style=\"font-family: helvetica, arial, sans-serif\">Although a core program covering the above-mentioned objectives has been designed for all participating sites, additional specific sub-projects are planned to prepare future follow-up projects. One subproject deals with record linkage with 1-year mortality and, in cooperation with health insurance companies, with the linking of data on drug use and adverse drug events (ADE) in outpatient care. A further subproject is working on a text body for Natural Language Processing (NLP) with regard to adverse drug reactions.<\/span><\/p>\n<p><span style=\"font-family: helvetica, arial, sans-serif\">The use case POLAR_MI will<\/span><\/p>\n<ul>\n<li><span style=\"font-family: helvetica, arial, sans-serif\">obtain data on drugs in Germany in the vicinity of university hospitals,<\/span><\/li>\n<li><span style=\"font-family: helvetica, arial, sans-serif\">demonstrate that effective use of these health data from MII centers in all four MII consortia can be made, and<\/span><\/li>\n<li><span style=\"font-family: helvetica, arial, sans-serif\">provide and validate a set of algorithms for classifying high-risk drugs and PIMs that can be used prospectively to improve drug safety.<\/span><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<p><\/p>\n<div class=\"accordion-group fau\">\n<h2 class=\"accordion-heading\"><button class=\"accordion-toggle\" data-toggle=\"collapse\"  href=\"#collapse_1\" aria-expanded=\"false\" aria-controls=\"collapse_1\" id=\"collapse_button_1\"> MIRACUM project partners <\/button><\/h2>\n<div id=\"collapse_1\" class=\"accordion-body\" aria-labelledby=\"collapse_button_1\">\n<div class=\"accordion-inner clearfix\">\n<ul>\n<li><span style=\"font-family: helvetica, arial, sans-serif\">Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg<\/span><\/li>\n<li><span style=\"font-family: helvetica, arial, sans-serif\">University Hospital Erlangen<\/span><\/li>\n<li><span style=\"font-family: helvetica, arial, sans-serif\">University Hospital Freiburg<\/span><\/li>\n<li><span style=\"font-family: helvetica, arial, sans-serif\">University Hospital Gie\u00dfen<\/span><\/li>\n<li><span style=\"font-family: helvetica, arial, sans-serif\">University Heidelberg, Medical Faculty Mannheim<\/span><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<p>\n<\/div>\n\n<h5><span style=\"font-family: helvetica, arial, sans-serif\">Further Information<\/span><\/h5>\n<p><a href=\"https:\/\/www.medizininformatik-initiative.de\/de\/POLAR\"><span style=\"font-family: helvetica, arial, sans-serif\">MII Website \u2013 POLAR_MI<\/span><\/a><\/p>\n<div class=\"shariff\"><ul class=\"shariff-buttons theme-default orientation-horizontal buttonsize-medium\"><li class=\"shariff-button mastodon shariff-nocustomcolor\" style=\"background-color:#563ACC\"><a href=\"https:\/\/s2f.kytta.dev\/?text=POLAR_MI https%3A%2F%2Fwww.miracum.org%2Fen%2Fdas-konsortium%2Fprojekte%2Fpolar_mi%2F\" title=\"Share on Mastodon\" aria-label=\"Share on Mastodon\" role=\"button\" rel=\"noopener nofollow\" class=\"shariff-link\" style=\"; 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background-color:#fff; color:#fff\" target=\"_blank\"><span class=\"shariff-icon\" style=\"\"><svg width=\"32px\" height=\"20px\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 11 32\"><path fill=\"#999\" d=\"M11.4 24v2.3q0 0.5-0.3 0.8t-0.8 0.4h-9.1q-0.5 0-0.8-0.4t-0.4-0.8v-2.3q0-0.5 0.4-0.8t0.8-0.4h1.1v-6.8h-1.1q-0.5 0-0.8-0.4t-0.4-0.8v-2.3q0-0.5 0.4-0.8t0.8-0.4h6.8q0.5 0 0.8 0.4t0.4 0.8v10.3h1.1q0.5 0 0.8 0.4t0.3 0.8zM9.2 3.4v3.4q0 0.5-0.4 0.8t-0.8 0.4h-4.6q-0.4 0-0.8-0.4t-0.4-0.8v-3.4q0-0.4 0.4-0.8t0.8-0.4h4.6q0.5 0 0.8 0.4t0.4 0.8z\"\/><\/svg><\/span><\/a><\/li><\/ul><\/div>","protected":false},"excerpt":{"rendered":"<p>Polypharmacy, Drug Interactions and Risks The Use Case \u201cPolypharmacy, Drug Interactions and Risks\u201d (POLypharmazie, Arzneimittelwechselwirkungen und Risiken), which includes all four consortia of the Medical Informatics Initiative, aims to contribute&hellip;<!--&hellip;--> <a class=\"more-link fa fa-angle-double-right\" href=\"https:\/\/www.miracum.org\/en\/das-konsortium\/projekte\/polar_mi\/\" title=\"Read more about &quot;POLAR_MI&quot;\"><\/a><\/p>\n","protected":false},"author":3748,"featured_media":0,"parent":6771,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_rrze_cache":"enabled","_rrze_multilang_single_locale":"en_US","_rrze_multilang_single_source":"https:\/\/miracum.cms.rrze.uni-erlangen.de\/?page_id=6230","footnotes":""},"page_category":[],"page_tag":[],"workflow_usergroup":[],"class_list":["post-6790","page","type-page","status-publish","hentry","en-US"],"_links":{"self":[{"href":"https:\/\/www.miracum.org\/wp-json\/wp\/v2\/pages\/6790","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.miracum.org\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.miracum.org\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.miracum.org\/wp-json\/wp\/v2\/users\/3748"}],"replies":[{"embeddable":true,"href":"https:\/\/www.miracum.org\/wp-json\/wp\/v2\/comments?post=6790"}],"version-history":[{"count":2,"href":"https:\/\/www.miracum.org\/wp-json\/wp\/v2\/pages\/6790\/revisions"}],"predecessor-version":[{"id":7445,"href":"https:\/\/www.miracum.org\/wp-json\/wp\/v2\/pages\/6790\/revisions\/7445"}],"up":[{"embeddable":true,"href":"https:\/\/www.miracum.org\/wp-json\/wp\/v2\/pages\/6771"}],"wp:attachment":[{"href":"https:\/\/www.miracum.org\/wp-json\/wp\/v2\/media?parent=6790"}],"wp:term":[{"taxonomy":"page_category","embeddable":true,"href":"https:\/\/www.miracum.org\/wp-json\/wp\/v2\/page_category?post=6790"},{"taxonomy":"page_tag","embeddable":true,"href":"https:\/\/www.miracum.org\/wp-json\/wp\/v2\/page_tag?post=6790"},{"taxonomy":"workflow_usergroup","embeddable":true,"href":"https:\/\/www.miracum.org\/wp-json\/wp\/v2\/workflow_usergroup?post=6790"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}