{"id":8187,"date":"2022-07-26T08:58:32","date_gmt":"2022-07-26T06:58:32","guid":{"rendered":"https:\/\/www.miracum.org\/?page_id=8187"},"modified":"2024-09-13T10:02:03","modified_gmt":"2024-09-13T08:02:03","slug":"medax","status":"publish","type":"page","link":"https:\/\/www.miracum.org\/en\/forschung\/nachwuchsforschergruppen\/medax\/","title":{"rendered":"MeDaX"},"content":{"rendered":"<h3><span style=\"font-family: helvetica, arial, sans-serif\">Development and implementation of innovative methods and tools for biomedical data exploration<\/span><\/h3>\n<h4><\/h4>\n<h4><span style=\"font-family: helvetica, arial, sans-serif\">About the project<br \/>\n<\/span><\/h4>\n<p style=\"text-align: justify\"><span style=\"font-family: helvetica, arial, sans-serif\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-8472 alignright\" src=\"https:\/\/www.miracum.org\/files\/2022\/09\/MeDaX_Logo.png\" alt=\"\" width=\"170\" height=\"169\" srcset=\"https:\/\/www.miracum.org\/files\/2022\/09\/MeDaX_Logo.png 170w, https:\/\/www.miracum.org\/files\/2022\/09\/MeDaX_Logo-150x150.png 150w, https:\/\/www.miracum.org\/files\/2022\/09\/MeDaX_Logo-60x60.png 60w\" sizes=\"auto, (max-width: 170px) 100vw, 170px\" \/>Evidence-based medicine uses high-quality, curated, and reliable data from health research, combines them with the respective individual expertise of the treating physicians and aims to make the best possible treatment decisions for individual patients. In order to generate the necessary knowledge from the accessible data sources, heterogeneous data must be combined and made comparable &#8211; a complex task from the perspective of data science. For a reliable data basis of high quality, good documentation of the research process and the resulting data is crucial. This also includes the process of integrating heterogeneous data from different sources, as the quality of the database depends to a large extent on the quality of the data sources, but no less on the quality of the data integration.<\/span><\/p>\n<hr \/>\n<h4><span style=\"font-family: helvetica, arial, sans-serif\">Goals<\/span><\/h4>\n<p style=\"text-align: justify\"><span style=\"font-family: helvetica, arial, sans-serif\">With a focus on the generation of FAIR data and the integration of standardized data formats, the junior research group MeDaX is developing an information and research platform for (bio)<strong>Me<\/strong>dical <strong>Da<\/strong>ta e<strong>X<\/strong>ploration. For this purpose,<\/span><\/p>\n<ol style=\"text-align: justify\">\n<li><span style=\"font-family: helvetica, arial, sans-serif\">heterogeneous (bio)medical data from various sources are merged into a knowledge graph (graph database) via so-called ETL processes (ETL: Extract-Transform-Load),<\/span><\/li>\n<li><span style=\"font-family: helvetica, arial, sans-serif\">new or improved methods for computer-aided semantic enrichment, quality control, provenance and comparability are developed, and<\/span><\/li>\n<li><span style=\"font-family: helvetica, arial, sans-serif\">algorithms and tools for further processing of the data are integrated.<\/span><\/li>\n<\/ol>\n<p style=\"text-align: justify\"><span style=\"font-family: helvetica, arial, sans-serif\">Various data sources, such as the Medical Informatics Initiative core data set, local population studies, biomedical ontologies, and publicly available information portals, will serve as starting points. In addition, the needs of patients and data-collecting physicians and scientists must be elicited during the set-up phase to ensure the greatest possible benefit from the MeDaX platform. <\/span><\/p>\n<p style=\"text-align: justify\"><span style=\"font-family: helvetica, arial, sans-serif\">The protection of personal data and the transparent documentation and communication of scientific work as the basis for sustainable science are particularly important to the group.<\/span><\/p>\n<hr \/>\n<h4><span style=\"font-family: helvetica, arial, sans-serif\">Lead of the Junior Research Group<\/span><\/h4>\n<p style=\"text-align: justify\"><div class=\"three-columns-one\"><p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-8394 size-medium-cropped\" style=\"border-radius: 200px;vertical-align: middle\" src=\"https:\/\/www.miracum.org\/files\/2022\/08\/MeDaX_Portrait_Wodke-e1661940891328-300x300.jpg\" alt=\"\" width=\"300\" height=\"300\" srcset=\"https:\/\/www.miracum.org\/files\/2022\/08\/MeDaX_Portrait_Wodke-e1661940891328-300x300.jpg 300w, https:\/\/www.miracum.org\/files\/2022\/08\/MeDaX_Portrait_Wodke-e1661940891328-150x150.jpg 150w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/p>\n<p style=\"text-align: justify\">\n<\/div><br \/>\n<div class=\"three-columns-two last\"><\/p>\n<h4><\/h4>\n<h4><\/h4>\n<p>&nbsp;<\/p>\n<h4><span style=\"font-family: helvetica, arial, sans-serif\">Dr. Judith Wodke<\/span><\/h4>\n<p><span style=\"font-family: helvetica, arial, sans-serif\"><strong>Leader of the Junior Research Group MeDaX<\/strong><\/span><br \/>\n<span style=\"font-family: helvetica, arial, sans-serif\"><em>Medical Informatics Laboratory &#8211; Institute for Community Medicine | University Hospital Greifswald<br \/>\n<\/em><\/span><\/p>\n<p><a href=\"mailto:judith.wodke@uni-greifswald.de\"><span style=\"font-family: helvetica, arial, sans-serif\">Contact<\/span><\/a><\/p>\n<p>&nbsp;<\/p>\n<p>\n<\/div><br \/>\n<div class=\"elements-divider\"><\/div><\/p>\n<hr \/>\n<h4><span style=\"font-family: helvetica, arial, sans-serif\">Team<\/span><\/h4>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-10415 size-full\" src=\"https:\/\/www.miracum.org\/files\/2024\/09\/MeDaX_team3.png\" alt=\"\" width=\"1678\" height=\"1144\" srcset=\"https:\/\/www.miracum.org\/files\/2024\/09\/MeDaX_team3.png 1678w, https:\/\/www.miracum.org\/files\/2024\/09\/MeDaX_team3-300x205.png 300w, https:\/\/www.miracum.org\/files\/2024\/09\/MeDaX_team3-1024x698.png 1024w, https:\/\/www.miracum.org\/files\/2024\/09\/MeDaX_team3-768x524.png 768w, https:\/\/www.miracum.org\/files\/2024\/09\/MeDaX_team3-1536x1047.png 1536w, https:\/\/www.miracum.org\/files\/2024\/09\/MeDaX_team3-60x41.png 60w, https:\/\/www.miracum.org\/files\/2024\/09\/MeDaX_team3-845x576.png 845w, https:\/\/www.miracum.org\/files\/2024\/09\/MeDaX_team3-1012x690.png 1012w\" sizes=\"auto, (max-width: 1678px) 100vw, 1678px\" \/><\/p>\n<hr \/>\n<div class=\"rrze-elements accordion style_default\" id=\"accordion-0\"><\/p>\n<div class=\"accordion-group fau\">\n<h2 class=\"accordion-heading\"><button class=\"accordion-toggle\" data-toggle=\"collapse\"  href=\"#collapse_0\" aria-expanded=\"false\" aria-controls=\"collapse_0\" id=\"collapse_button_0\"> Publikationen <\/button><\/h2>\n<div id=\"collapse_0\" class=\"accordion-body\" aria-labelledby=\"collapse_button_0\">\n<div class=\"accordion-inner clearfix\">\n<p><span style=\"font-family: helvetica, arial, sans-serif\">Journal publications<\/span><\/p>\n<ul>\n<li><span style=\"font-family: helvetica, arial, sans-serif\">Lobentanzer et al.<a href=\"https:\/\/www.nature.com\/articles\/s41587-023-01848-y\"> Democratizing knowledge representation with BioCypher.<\/a> Nat Biotech. 2023;41:1056\u20131059.<\/span><\/li>\n<li><span style=\"font-family: helvetica, arial, sans-serif\">Waltemath et al. <a href=\"https:\/\/link.springer.com\/article\/10.1007\/s00103-024-03884-8\">FAIRe Gesundheitsdaten im nationalen und internationalen Datenraum.<\/a><\/span><\/li>\n<li><span style=\"font-family: helvetica, arial, sans-serif\">Ammon &amp; Kurscheidt et al. <a href=\"https:\/\/link.springer.com\/article\/10.1007\/s00103-024-03888-4\">Arbeitsgruppe Interoperabilit\u00e4t: Kerndatensatz und Informationssysteme f\u00fcr Integration und Austausch von Daten in der Medizininformatik-Initiative.<\/a> Bundesgesundheitsblatt. 2024; 67:710\u2013720.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-family: helvetica, arial, sans-serif\">Conference papers<strong><br \/>\n<\/strong><\/span><\/p>\n<ul>\n<li><span style=\"font-family: helvetica, arial, sans-serif\">Wodke JAH et al. <a href=\"https:\/\/doi.org\/10.3233\/SHTI230089\">The MeDaX Knowledge Graph Prototype.<\/a> Stud Health Technol Inform. 2023 May 18;302:147-148.<\/span><\/li>\n<li><span style=\"font-family: helvetica, arial, sans-serif\">Gierend K, Judith A.H. et al. T<a href=\"https:\/\/doi.org\/10.1145\/3543873.3587562\">APP: Defining standard provenance information for clinical research data and workflows &#8211; Obstacles and opportunities.<\/a> In Companion Proceedings of the ACM Web Conference 2023 (WWW &#8217;23 Companion). Association for Computing Machinery, New York, NY, USA, 1551\u20131554.<\/span><\/li>\n<li><span style=\"font-family: helvetica, arial, sans-serif\">Mazein I et al. <a href=\"https:\/\/doi.org\/10.3233\/SHTI240423\">MeDaX: A Knowledge Graph on FHIR.<\/a> Stud Health Technol Inform. 2024 Aug 22;316:367-371.<\/span><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<div class=\"shariff\"><ul class=\"shariff-buttons theme-default orientation-horizontal buttonsize-medium\"><li class=\"shariff-button mastodon shariff-nocustomcolor\" style=\"background-color:#563ACC\"><a href=\"https:\/\/s2f.kytta.dev\/?text=MeDaX https%3A%2F%2Fwww.miracum.org%2Fen%2Fforschung%2Fnachwuchsforschergruppen%2Fmedax%2F\" title=\"Share on Mastodon\" aria-label=\"Share on Mastodon\" role=\"button\" rel=\"noopener nofollow\" class=\"shariff-link\" style=\"; background-color:#6364FF; color:#fff\" target=\"_blank\"><span class=\"shariff-icon\" style=\"\"><svg width=\"75\" height=\"79\" viewBox=\"0 0 75 79\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M37.813-.025C32.462-.058 27.114.13 21.79.598c-8.544.621-17.214 5.58-20.203 13.931C-1.12 23.318.408 32.622.465 41.65c.375 7.316.943 14.78 3.392 21.73 4.365 9.465 14.781 14.537 24.782 15.385 7.64.698 15.761-.213 22.517-4.026a54.1 54.1 0 0 0 .01-6.232c-6.855 1.316-14.101 2.609-21.049 1.074-3.883-.88-6.876-4.237-7.25-8.215-1.53-3.988 3.78-.43 5.584-.883 9.048 1.224 18.282.776 27.303-.462 7.044-.837 14.26-4.788 16.65-11.833 2.263-6.135 1.215-12.79 1.698-19.177.06-3.84.09-7.692-.262-11.52C72.596 7.844 63.223.981 53.834.684a219.453 219.453 0 0 0-16.022-.71zm11.294 12.882c5.5-.067 10.801 4.143 11.67 9.653.338 1.48.471 3 .471 4.515v21.088h-8.357c-.07-7.588.153-15.182-.131-22.765-.587-4.368-7.04-5.747-9.672-2.397-2.422 3.04-1.47 7.155-1.67 10.735v6.392h-8.307c-.146-4.996.359-10.045-.404-15.002-1.108-4.218-7.809-5.565-10.094-1.666-1.685 3.046-.712 6.634-.976 9.936v14.767h-8.354c.109-8.165-.238-16.344.215-24.5.674-5.346 5.095-10.389 10.676-10.627 4.902-.739 10.103 2.038 12.053 6.631.375 1.435 1.76 1.932 1.994.084 1.844-3.704 5.501-6.739 9.785-6.771.367-.044.735-.068 1.101-.073z\"\/><defs><linearGradient id=\"paint0_linear_549_34\" x1=\"37.0692\" y1=\"0\" x2=\"37.0692\" y2=\"79\" gradientUnits=\"userSpaceOnUse\"><stop stop-color=\"#6364FF\"\/><stop offset=\"1\" stop-color=\"#563ACC\"\/><\/linearGradient><\/defs><\/svg><\/span><span class=\"shariff-text\">share<\/span>&nbsp;<\/a><\/li><li class=\"shariff-button facebook shariff-nocustomcolor\" style=\"background-color:#4273c8\"><a href=\"https:\/\/www.facebook.com\/sharer\/sharer.php?u=https%3A%2F%2Fwww.miracum.org%2Fen%2Fforschung%2Fnachwuchsforschergruppen%2Fmedax%2F\" title=\"Share on Facebook\" aria-label=\"Share on Facebook\" role=\"button\" rel=\"nofollow\" class=\"shariff-link\" style=\"; 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