Author Archive:Maximilian Karg

ByMaximilian Karg

MIRACUM’s Prof. Dr. Sedlmayr appointed as a member of The National Expert Committee for Interoperability in the Healthcare Sector

In a recent press release gematik announces the start of the work of The National Expert Committee for Interoperability in the Healthcare Sector.

We are very pleased to have Prof. Dr. Sedlmayr, Professor of Medical Informatics, TU Dresden, with research interests in Intelligent Information Systems (process-oriented and knowledge-based systems), Communication Systems and Knowledge Management, as one of the renowned experts on this board.

The National Expert Committee on Healthcare Interoperability is an entity under the Health IT Interoperability Governance Regulation (HIGV). The body has been newly established and will start work for the first time in 2022. Its task will be to promote interoperability in the German healthcare system independently, transparently and with commitment. To this end, standards will not simply be listed. Rather, needs and possible solutions will be identified and recommended. In doing so, it will also be important to consider the framework conditions under which the standards can develop their potential.

After all, there is no shortage of standards. Rather, they need to be meaningfully combined and further developed in such a way that they enable collaboration in the healthcare system to be safe, effective and efficient. As a representative of science, I am pleased to be able to contribute to this responsible and important task.”, says Prof. Dr. Sedlmayr.

The nominated experts have accepted their appointment by gematik in agreement with the Federal Ministry of Health. The initial membership of the seven-member expert panel combines many years of expertise, medical practice experience, and diversity as a group. The seven full members are:

  • Anke Diehl, MD, Chief Transformation Officer (CTO), Essen University Hospital.
  • Simone Heckmann, Chief Executive Officer (CEO), Gefyra
  • Dr. med. Siegfried Jedamzik, Managing Director, Bayerische TelemedAllianz (BTA)
  • Dr. med. Sylvia Thun, Director of Digital Medicine and Interoperability, BIH@Charite – Universitätsmedizin Berlin
  • P. H. Susanne Ozegowski, Head of Corporate Development, TK
  • Jörg Studzinski, Project Manager Digitalization, AGAPLESION MITTELDEUTSCHLAND
  • Dr. rer. nat. Dr. habil. med. Martin Sedlmayr, Professor of Medical Informatics, TU Dresden

Prof. Dr. Sylvia Thun was elected chairperson by the group and is looking forward to the responsible task and cooperation. Stefan Höcherl, Head of Strategy & Standards at gematik, is responsible for the Coordination Office for Interoperability and thus for the cooperation with the expert body.

MIRACUM wishes all members much success in their upcoming tasks and in achieving the goal of binding and internationally recognized standards in the German health care system.

→ Read the official press release for more information.


gematik goals: A digital healthcare infrastructure for Germany

gematik bears overall responsibility for the telematics infrastructure (TI), the central platform for digital applications in the German healthcare system. By defining and enforcing binding standards for services, components and applications in the TI, gematik ensures that this central infrastructure is and remains secure, efficient and user-friendly.

ByMaximilian Karg

Start of the new junior research group EkoEstMed at the Albert-Ludwigs University of Freiburg!

Under the leadership of Dr. Geoffroy Andrieux, the junior research group “Entwicklungen von klinisch-orientierten Entscheidungsunterstützungen für Hochdurchsatzdaten in der personalisierten Medizin (EkoEstMed)” (engl.: Developments of clinically-oriented decision support for high-throughput data in personalised medicine) has started its work at the Albert-Ludwigs University of Freiburg on December 15th 2021.

Nowadays, precision medicine is becoming more and more of a reality and is moving further and further into everyday clinical practice. Unique characteristics of patients are identified to improve the effectiveness and accuracy of their treatments. Ambitious initiatives such as the “Medical Informatics Initiative ” (MII) actively support biomedical research in Germany to improve individualised patient care. It relies heavily on the ever-growing amount of health-related data and constantly evolving technologies. However, due to a lack of analytical methods and standardisation and harmonisation processes, only part of the existing data is used for clinical recommendations. Thus, the goal is to process and present the complex data in a comprehensible form through the development of innovative methods, such as machine learning (artificial intelligence) algorithms, and analysis processes, while at the same time making them available for exchange in an efficient and usable manner. In addition, efficient IT infrastructures as well as the development of novel visualisation standards will be created to ensure implementation and application in the clinic. This project will not only advance the processes of personalised medicine in the local clinical setting, but also MII and MIRACUM at various sites.

What are the objectives?

  1. Methods for the development, provision and use of Omics data

The aim is to develop standardisation methods to properly store, annotate and share the resulting Omics/high-throughput data, and at the same time to develop visualisation methods to process and use this high-dimensional data for clinical applications.

  1. Integration of multi-Omics data

The integration of Omics data, which on the one hand originate from different clinical laboratories and on the other hand can be used from public databases, is usually accompanied by possible batch effects. For this purpose, appropriate methods and approaches of batch effect correction will be developed and applied, and at the same time other co-factors such as gender, age and environment will be taken into account. In addition, correlation and interaction analyses of the different omics data sets will be applied and further developed, which will ultimately lead to a score for the assessment of pathogenicity.

  1. Development of tools for decision support in the clinical context

The aim is to identify molecular features that may influence treatment recommendations and disease outcome and response to treatment. Therefore, the group aims to estimate the likelihood of developing a particular type of cancer or the likelihood of recurrence and ultimately life expectancy.

ByMaximilian Karg

New interview film of the Medical Informatics Initiative: Strengthening research and advancing healthcare

What does medical informatics actually mean for patients and how does it help doctors both in practice and in data-based medical research? In the new interview film of the Medical Informatics Initiative (MII), funded by the German Federal Ministry of Education and Research, people now have their say with their personal experiences. Patients talk about the possibilities and future prospects with the help of modern medical informatics and specialists explain the advantages in their work.

ByMaximilian Karg

Federal Ministry of Education and Research (BMBF) confirms positive progress in the development of the MII Data Integration Centres through external audit.

According to the external auditors, essential foundations and organisational structures have already been created. In addition, the sites have relevant concepts for further development of the data infrastructure, data management and compliance with data protection regulations. “Already one and a half years before the end of the set-up and networking phase of the MII and despite the great strain on the university hospitals during the Corona pandemic, 90 percent of the sites were assessed as well advanced or advanced,” the BMBF announcement reads.

Details can be found in the official press release of the Medical Informatics Initiative and in a recent announcement regarding the external auditing process of the Federal Ministry of Education and Research.

ByMaximilian Karg

The medical informatics consortia MIRACUM and SMITH cooperate: Trusted Third Party Greifswald supplies software and officially supports SMITH sites in using gICS® and gPAS®

Networking and harmonisation of infrastructures in collaborative medical research is taking place in a very practical way. The consortium leaders Prof. Dr. Markus Löffler (SMITH) and Prof. Dr. Hans-Ulrich Prokosch (MIRACUM), as well as representatives of the Trusted Third Party of the University Medicine Greifswald (THS Greifswald), have confirmed their will to work together on data protection issues in an Letter of Intent. The MIRACUM site in Greifswald will provide software tools as work results for SMITH for subsequent use and support SMITH in their practical use.

In the context of the Medical Informatics Initiative (MII), the preservation of data protection and the associated topics such as record linkage, pseudonymization and consent management are of central importance. The SMITH consortium provides for corresponding components in its reference architecture of a data integration center.

In the MII, the THS Greifswald, as a MIRACUM partner, already provides various tools for setting up Trusted Third Party solutions as building blocks of the MIRACOLIX toolbox.

The software tools gPAS® and gICS® fit well with the reference architecture in SMITH and fulfil the technical requirements of the consortium. The tools gPAS® and gICS® will therefore be used for the pseudonymization and consent management components of the reference architecture of the SMITH data integration centers. Within the framework of the THS community dialogue organized by the Greifswald partner, there is a joint exchange on the software tools with the aim of promoting the broad use of these tools in the MII and other projects, e.g. NUM.

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