Before the start of the development and networking phase of the MIRACUM project in January 2018, the University Medicine of Mannheim and the University of Applied Science of Mannheim celebrate the funding of the MIRACUM consortium. The MIRACUM partners will present the basic structures and contents of the MIRACUM projects to local representatives in Mannheim. In addition, they will discuss the possibility of integrating the regional health landscape and of networking with the representatives of the Metropolregion Rhein-Neckar, DE:HUB and the office for urban development and cluster management.
Today the Federal Ministry of Education and Research (BMBF) has announced that the MIRACUM consortium will receive a funding of €32.1 Mio for its concept of establishing data integration centres (DIC) by implementing use cases to apply data from the respective DIC in research and care and for its concept of strengthening medical informatics in Germany.
Four out of the seven consortia, which have started into the MI-I conceptual phase in 2016, have now been selected for the MI-I development and networking phase by an international jury of experts in the fields of medicine and medical informatics. The funding period of four years will start in January 2018.
MIRACUM – this is eight universities with eight university hospitals, two universities of applied sciences and one industrial partner spread over five German states. A major focus is on the establishment of data integration centres to link and exchange data of the eight university hospitals. Data protection and data security are given top priority in this venture.
Johanna Wanka, Minister of Education and Research, envisions that „every physician, no matter whether he/she is working in a hospital or as a general practitioner or as a medical specialist, can retrieve all the experience and research results available at the touc h of a button, to include this information into his/hertherapeutic decision. By doing so, the therapy and the counselling of patients will still get better in the future“.
First results have already illustrated the opportunities which arise from the federated analysis of data within the eight MIRACUM DIC. A cohort of stroke patients has been identified and the adherence of clinicians to the recently modified stroke guidelines has been analyzed. In a second small project and together with the HD4CR consortium, real-world clinical pathways have been analyzed for more than 18.000 colorectal cancer patients of eleven maximum care hospitals.
BMBF press report: https://www.bmbf.de/de/bessere-therapien-dank-medizininformatik-4473.html
The TH Mittelhessen announces a W2 professorship with the focus on e-Health and Medical Data Science to boost the team of medical informatics in Gießen. The candidate is expected to hold proficiencies in at least one of the four topics:
Further information is provided in the job posting of the TH Mittelhessen.
In collaboration with the German Cancer Research Center (DKFZ), the Medical Faculty of the Goethe-University announces a new W2 professorship for “Bioinformatics in Oncology” in Frankfurt. Within the field of bioinformatics, she/he will be focussing on oncogenic signal transduction, systems biology and medicine (e.g. data integration) as well as on high throughput experimentation, especially in proteomics. The position will be located at the University Hospital Frankfurt and collaborate with the scientific and clinical research community of the DKTK (www.dktk.org), the DKFZ (www.dkfz.de) and the DKTK partner site Frankfurt / Mainz.
The integration of clinical decision support systems for pharmacogenomic testing into clinical routine has been investigated by the MIRACUM consortium over the last nine months. This joint effort has now resulted in a scoping literature review accepted by BMC Medical Informatics and Decision Making. A total of 12 authors from nine MIRACUM sites provide an overview of the designs of user-system interactions in recent system developments. The final analysis comprises the essence of 32 articles that were identified in a PubMed search. As the most widespread tool, alerts have been identified, next to pharmacogenomic reports, inbox messages, and several more. The authors conclude that i) further evaluation efforts of developed prototypes will be necessary and ii) in the future clinical decision support systems will include prediction models to identify eligible patients for pre-emptive genotyping.
Hinderer M, Boeker M, Wagner SA, Lablans M, Newe S, Hülsemann JL, Neumaier M, Binder H, Renz H, Acker T, Prokosch HU, Sedlmayr M.
Integrating clinical decision support systems for pharmacogenomic testing into clinical routine – a scoping review of designs of user-system interactions in recent system development.
BMC Med Inform Decis Mak. 2017 Jun 6;17(1):81. DOI: 10.1186/s12911-017-0480-y.
The Medical Faculty of the Otto-von-Guericke-University Magdeburg aims at promoting its digital infrastructure in the fields of Medical Informatics and announces two new professorships: one W2 Professor for Biostatistics and one W3 Professor in Epidemiology and Health System Research. The latter will hold the position of Director of the Institute for Epidemiology and Health System Research. Please refer to the linked documents for more details.
The second joint project results of the MIRACUM consortium got accepted for publication in Pharmacogenomics. A project team of 11 of our MIRACUM partners has performed a survey among the clinicians of eight German university hospitals to assess the physicians’ attitude, their knowledge and their experience in pharmacogenomic clinical decision support. Overall, 564 physicians of 13 different medical specialties participated. The authors concluded that physicians in German hospitals require additional education of both genetics and pharmacogenomics. Furthermore, the physicians are mostly inexperienced in pharmacogenomic clinical decision support systems (CDSS) but need to be provided with access to relevant pharmacogenomic CDSS.
Hinderer M, Boeker M, Wagner SA, Binder H, Ückert F, Hülsemann JL, Neumaier M, Schade-Brittinger C, Acker T, Prokosch HU, Sedlmayr B. The experience of physicians in pharmacogenomic clinical decision support within eight German University Hospitals. Pharmacogenomics 2017.
After nine month of intense work with more than 100 MIRACUM team members contributing to the various pilot projects and to the MIRACUM grant proposal for the BMBF MI-I networking and developing phase MIRACUM version 0.9 has just been released.
We are proud that we have already achieved two joint MIRACUM publications and implemented a Version 0.9 data sharing infrastructure based on eight DIC implementation. In the last three weeks we could even extend this data sharing network in a cross-consortia cooperation with HD4CR, resulting in distributed proof-of-concept analysis based on 11 i2b2 and OMOP research data repository instances.
We thank all our MIRACUM team members for their tremendous engagement in the last nine month – you are a great team!
We are looking forward to leverage the value of our eight DIC data together in future research projects
Stefanie Knöpfel, Ulli Prokosch and the Erlangen MIRACUM team
Six members of our MIRACUM consortium held a workshop on the 25th of April 2017 at the conhIT 2017 in Berlin. They presented the current BMBF funding scheme “medical informatics” as well as the most recent areas of research activities of the MIRACUM consortium. As head of the workshop, Paul Schmücker introduced the current BMBF funding scheme “medical informatics” and lead through the workshop session. Martin Lablans provided the audience with an insight into medical data sharing and its tremendous importance for the German healthcare. Following this, Thomas Ganslandt illustrated both the development and the implementation of data repositories for data sharing. The fourth speaker was Jan Christoph describing both how to integrate omics data into clinical data and what might be most challanging to achieve this. Last but not least, Marc Hinderer presented the latest research results of the MIRACUM consortium regarding clinical decision support for molecular tumor boards.
In autumn 2016 the University of Applied Sciences Mannheim has issued a W2 professorship for “Medical Data Science”. Dr. Ulrike Kutscha (Heidelberg) accepted the call on April 10th, 2017. She will start her work at Mannheim University of Applied Sciences on September 1st, 2017.
We can also announce the next W2 professorship that has been released by the University Medical Center of the Johannes-Gutenberg-University Mainz. The new professor will lead the group of Medical Informatics at the Institute for Medical Biometry, Epidemiology and Informatics (IMBEI). A major focus will be the conceptual design and implementation of a data integration centre. Based on data from patient care and health insurances, research on health services as well as clinical and translational research shall be pursued.